Author: Jacobj, Carl [1857-1944]
Title: Beiträge zur physiologischen und pharmakologischen Kenntniss der Darmbewegungen mit besonderer Berücksichtigung der Beziehung.,.
Description: Leipzig, Verlag von F.C.W. Vogel, 1892. quarter-cloth. 23x16cm, Contemporary binder's blind quarter-cloth. Paper spine label. Weighs 900 grams.. Rubbed. Front interior hinge crack. Good. ¶ Offered here is the complete volume 20 of "Archiv für experimentelle Pathologie und Pharmakologie" edited by B. Naunyn & O. Schmiedeberg [vi,472pp], which contains Jacobj's paper "Beiträge zur physiologischen und pharmakologischen Kenntniss der Darmbewegungen mit besonderer Berü cksichtigung der Beziehung der Nebenniere zu denselben" [pages 171-211], " the first indirect demonstration of the role of the adrenal medulla as an endocrine organ" + one other paper by Jacobj ["Ueber das Functionsvermögen der künstlich durtchblutteten Niere"] + 21 other papers by various authors.["In the early 1890s, the German pharmacologist Carl Jacobj in the laboratory of Oswald Schmiedeberg in Strasbourg studied the relationship between the adrenals and the intestine. Electrical stimulation of the vagus nerve or injection of muscarine elicited peristalsis. This peristalis was promptly abolished by electrical stimulation of the adrenals. The experiment has been called 'the first indirect demonstration of the role of the adrenal medulla as an endocrine organ actually a more sophisticated demonstration of the adrenal medullary function than the classic study of Oliver and Schäfer'. While this may be true, Jacobj did not envisage a chemical signal secreted into the blood to influence distant organs, in other words a hormone, but nerves running from the adrenals to the gut, 'Hemmungsbahnen für die Darmbewegung'..." - from " History of catecholamine research", wikipedia].

Keywords: History of Medicine, Adrenal medulla, Physiology, Adrenals, , , , ,

Price: US$ 89.00 Seller: Expatriate Bookshop of Denmark
- Book number: BOOKS026620I