Author: Kalckar, Herman Moritz [1908-1991]
Title: Fosforyleringsprocesser i dyrisk væv
Description: København, Nyt Nordisk Forlag, 1938. orig.wrappers. 24x16cm, 138 pp. Some small tears to wrapper edges. University of Copenhagen doctoral dissertation. Includes a 12-page English summary.. Rubbed. Spine chipped & torn. Good ¶ Inscribed by author on half-title: "Hr. og Fru Crawford / med venlig hilsen / fra forf." ["...a Danish biochemist who pioneered the study of cellular respiration. Kalckar made a number of significant contributions to the development of 20 th century biochemistry including: a founder of bioenergetics; enzymology, including novel assay techniques; galactose metabolism in both microorganisms and animal tissues; suggestion that strontium-90 levels in children’s deciduous teeth correlated with nuclear testing....Kalckar completed his medical training at the University of Copenhagen in 1933, and then began research for his Ph. D. in Ejnar Lundsgaard's physiology laboratory; that work established the foundation of a fundamental biochemical paradigm, i.e. 'oxidative phosphorylation'. During this period, Lundsgaard was preoccupied as physiology department chair, consequently Fritz Albert Lipmann, who had recently fled Germany, served as Kalckar's research mentor. Later, Kalckar and Lipmann both independently developed concepts of a 'high energy bond' ..Kalckar's breakthrough work was the demonstration that organic compounds, which were phosphorylated during metabolic processes, involved oxygen consumption; oxygen consumption was linked to organic compound phosphorylation. His key experiment demonstrated that in frog muscles where glycolysis had been inhibited with iodoacetate, muscular contraction continued for a short period using phosphocreatine as a source of energy. Kalckar referred to this process as 'aerobic phosphorylation' ..." -wikipedia].

Keywords: Biochemistry, Physiology, History of Science, , , , , ,