Author: Fibiger, Johannes Andreas Grib [1867-1928] ; & Møller, Poul
Title: Investigations upon Immunisation Against Metastasis Formation in Experimental Cancer
Description: København, A.F. Høst & Søn, 1927. orig.wrappers. 24x15cm, 30,(5) pp. Unopened. Some browning to wrapper edges.. 5pp photoplates.. Some rubbing. Some small tears & chips to wrapper edges. Good. ¶ Includes 5pp single-side photoplates [4 folding]. Series: Det. Kgl. Danske Videnskabernes Selskab, Biologiske Meddelelser, VI, 4. [" Fibiger...won the 1926 Nobel Prize in Physiology or Medicine. Fibiger had claimed to find an organism he called Spiroptera carcinoma that caused cancer in mice and rats. He received Nobel prize for this discovery. Later, it was shown that this specific organism was not the primary cause of the tumors. Moreover, Katsusaburo Yamagiwa, only two years later in 1915 has successfully induced squamous cell carcinoma by painting crude coal tar on the inner surface of rabbits' ears. Yamagiwa's work has become the primary basis for this line of research. Because of this, some consider Fibiger's Nobel Prize to be undeserved particularly because Yamagiwa did not receive the prize. But others credit Fibiger with showing that external stimuli can induce cancer and proving the correlation by experimental method.... While studying tuberculosis in lab rats, Fibiger found tumors in some of his rats. He discovered that these tumors were associated with parasitic nematode worms that had been living in some cockroaches that the rats had eaten. He thought that these organisms may have been the cause of the cancer. In fact, the rats had been suffering from a vitamin A deficiency and this was the main cause of the tumors....One of his experiments from 1898 is by some regarded as the first controlled clinical trial...." - wikipedia].

Keywords: Experimental Neoplasms, Nobel Prize, Oncology, Cancer, History of Medicine, Spiroptera, Cell Carcinoma, ,