Author: KÜHNE, W. (F.)
Title: Zur Photochemie der Netzhaut. Idem, Ueber den Sehepurper.
Description: Heidelberg, C.Winter, 1877. - 1878. W. 1 lith. plate. In 4 parts. Original uniform pink pr. wr. (some soiling). (pp. 1 - 14; 15 - 103). (Published in: 'Untersuchingen Phys. Inst. Heidelberg', vol. I, in 4 parts.). (Uncut.). (Unopened.). (Edges some foxed spots & light surface soiling.). DSB vol. VII, pp. 519 - 521: 'In 1876 Boll had established that the layer of rods of the retina contain a purple pigment that disappears on exposure to light. On this basis Kühne supposed that there was a primarily chemical process that preceded excitation of the optic nerves, he demonstrated that the retina works like a photographic plate, with light bleaching out the visual purple, which is regenerated in darkness. He succeeded in producing his famous "optograms" - the reproduction of the pattern of crossbars of a window on the chemical substance of the retina of a rabbit... Kühne was thus the first to perceive the migrating pigments in the living retina.': G&M 1519: 'Kühne was professor of physiology at Amsterdam and Heidelberg. Among his best work is his investigation of visual purple (rhodopsin) which he was first to extract from the retina. Several other papers by him on the same subject appear in the above volume.': Albert, e.a. Source Book, 1275: 1837 - 1900, physiologist, director of the physiological Institute at Heidelberg. An authority on muscle and nerve physiology.: Becker coll. item 221: 'Together they ['Netzhaut' and 'Sehpurpur'] represent Kühne's earliest complete statement regarding his researches on rhodopsin.': Gorin, p. 508: Rotschuh, 1859: Survey of contents of parts 2, 3 and 4 available on request.

Keywords: ophthalmology medicine W28 W72 Doos37