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MOBIUS, P[AUL] J[ULIUS] (1853-1907), Basedow'sche Krankheit.
Vienna: Alfred Holder, 1896. 1st Edition. [6]+121+[1]pp. Contemporary leather-backed marbled boards. Lacking the backstrip, light edgewear, a good copy only with The Hartford Retreat's gold foil stamp to the title-page. Scarce. Basedow's disease (named after the German physician Karl Basedow [1799-1854] who described it in 1840), also commonly known as Grave's disease after the English physician who had described it five years before Basedow, remained an etiological enigma through much of the 19th century, usually being construed as a neurological disease. It was Mobius who first attributed its symptoms of exophthalmic goiter to the thyroid gland's hyperthyroidism, which Mobius had first suggested in an 1886 paper. Strumpell, the leading German internist of his day, thought it was Mobius's greatest clinical achievement "to have erected, with one single stroke, the fruitful etiological concept in the place of all those previous contradictory and unsatisfactory attempts at explaining Graves' (or Basedow's) disease. A substance produced by the thyroid causing Graves' disease and antagonistic to the agent causing myxedema? This concept was so radical that Mobius' account of it in the twenty-second volume of Nothnagel's omnibus on internal medicine was presented in a separate monograph. Another author's account of 'diseases of the thyroid' covered only myxedema and cretinism. Endocrinology as such was not yet conceived; the term itself was coined only in 1909 by Nicola Pende" [Francis Schiller, A Mobius Strip: Fin-de-Siecle Neuropsychiatry and Paul Mobius, pp. 4-5]. Weight: 1 pound 1.0 ounces = 484 grams. Size: 10.0 x 6.8 x 0.5 inches = 25 x 17 x 1.3cm. Binding: HB.
Offered for US$ 85.00 by: John Gach Books - Book number: 072104
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